Precision Medicine Helps Conquer Advanced-Stage Cancer
–News Direct–
As North America reports a dramatic rise in advanced-stage cancer cases, experts are saying that major breakthroughs in oncology could make now the best time in human history to get cancer.
According to Miyo Yamashita, President and CEO of The Princess Margaret Cancer Foundation, in the last five to 10 years, our understanding of cancer has surpassed what we learned in the preceding 50 years.
Yamashita emphasized progress in molecular research, genomic sequencing, and personalized therapies surpassing conventional methods like surgery, radiation, and chemotherapy.
For cancer survivor Jenny Young, precision medicine has been life changing. Unlike one-size-fits-all treatments, precision medicines consider genetic variabilities in individual cancer cases.
At 41, she discovered a lethal tumor during a post-wedding world tour. Initially attributing symptoms to exhaustion, declining health led her to seek medical assistance.
Despite a stage four cancer diagnosis, traditionally deemed terminal, recent breakthroughs in cancer care altered Young's prognosis. Treatment options extended her life beyond the initial four to six weeks projected by doctors, challenging the perception of her survival as a mere miracle.
The answer was a life-saving cancer medicine called Osimertinib, marketed under the brand name Tagrisso. The medication works by attaching to a EGFR protein in cancer cells and stopping its activity, which helps prevent the cancer from growing.
Young has been taking the medication for four years now and while it won't cure her, it can effectively contain the issue for the time being. Acknowledging the pervasive impact of cancer, she expressed hope in innovative treatments, citing clinical trials.
Among the companies developing therapies for the expanding oncology market is Defence Therapeutics Inc. (CSE:DTC) (OTC:DTCFF), a Canadian biopharmaceutical company specializing in cancer vaccines and drug delivery technologies. The company collaborates with the academic laboratory of Dr. Moutih Rafei, a globally recognized expert in immuno-oncology, to advance the development of next-generation vaccines and Antibody-Drug Conjugate (ADC) products.
At the heart of Defence Therapeutics platform is its ACCUM technology, which enables precision delivery of vaccine antigens to target cells, enhancing the effectiveness and strength of treatments against severe illnesses like cancer and infectious diseases. This innovative technology has demonstrated the capability to deliver treatments at a rate ten times faster than other approved solutions, marking a significant advancement in the field.
Defence Therapeutics Submits IND to the FDA for Anti Cancer Drug
On November 14, Defence Therapeutics Inc. (CSE:DTC) (OTC:DTCFF) hit a major milestone with the successful submission of an Investigational New Drug (IND) application to the US Food and Drug Administration (FDA) for its injectable anticancer molecule AccuTOX for the treatment of solid tumors.
AccuTOX, evolving from the original Accum molecule, combats cancer by disrupting cell processes, blocking DNA repair in cancer cells, and triggering a cell death that activates the immune system. In studies led by Dr. Moutih Rafei, AccuTOX significantly reduced tumor growth in animals, achieving a survival rate of 70-100% in cases of lymphoma, melanoma, and breast cancer.
The IND application for Defence Therapeutics' AccuTOX includes comprehensive data on its pharmacological effects, safety in both laboratory and animal cancer models, and details on its production for human clinical trials. This application is aimed at demonstrating to the FDA the safety of AccuTOX for initial human administration.
With FDA approval, Defence Therapeutics could begin Phase I clinical trials as early as the first or second quarter of 2024.
Click here or visit their website for more information about Defence Therapeutics Inc. (CSE:DTC) (OTC:DTCFF).
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